Mike,
I have found that shooting a bow with a medium to high wrist configuration works very well, however I actually bear down against the palmswell as if I were attempting to shoot low wrist. The reason for this is that my recurve is a fairly long 62" and if I am wearing heavy clothing for late season deer hunting, my jacket will otherwise interfere with the string due to the shallow string angle. This is obviously a matter of practicality, and as far as "feel" or comfort, I believe one can adapt to any bow grip that works for them as long as their specific bow and shooting form preclude clothing interferance.
"Aman who is under 30, and is not a liberal hasn't heart, and a man who is over 30, and is not a conservative has no brains." -Sir Winston Churchill