This is what Mick Baker and Andy Ivy recommend, and I agree: Minimum 70 pound bow and 800+ grain arrows with solid 2 blade broadhead. Specific equipment choice in this range is also important. If you can COMFORTABLY shoot a 75 or 80 pound bow, go for it, along with 900+ grain arrows and hell-for-stout broadheads. Remember also that draw length is very important in getting full potential from your setup. If you have specific gear in mind, let us know and we can comment on it.
Allan