So many factors as Pearly mentioned but generally 1/2" at mid-limb will get you what you want with most woods, including Osage. Personally, I think we need a certain amount of compression value and I think 1/2" is about right for bows 60-64" and between 45-55#. You can start out wide, maintain 1/2" thickness and narrow to the weight you want. These are some of the guide lines I use.......Art