My experience is that length has a greater effect on tuning than tip weight. I use tip weight to tune when I’m very close to being in tune, and just need a little nudge one way or the other. You didn't tell us the length of the arrow you tried, so I don't know how much length you have to work with. I’m not familiar with the 45/60 spine. The old 35/55 converted into the modern .500, so I assume .500 is weaker than 45/60, but maybe not by much. Of course, another thing we don't know is how far out of tune the arrow you have is with a 300 grain tip, so I’ll “assume” it was close to being in tune. I think if you have 2” to work with, it would be worth trying a .500 spine full length with the 200 grain tip you want to use.