Strand count can make a difference on some bows. I've noticed a big difference witn one material--8125--on my personal bow. With 18 strands, it's very noisy. With 14 strands, it was super quiet--go figure.
Some bows just "like" some strings, or "dislike" some (my bow is quiet with just about anything other than 18 strands of 8125).
How the string is made, brace height, nock fit, release, arrow weight, arrow spine (changing strings may require you to change arrow spine), type material, number of strands, etc. etc. etc. can all have an effect.
Chad