Well let me say this, as a B-50 proponent, I have been using a 450 string from a fellow Tradganger now for several weeks and many hundred shots on a 67 Shakespeare Necedah. It's 8 strands with padded loops, and it made a big difference in vibration.
It also gave me about 8 yards longer for a point-on with my anchor.
I chose to give it a try since I don't have a lot invested in the Necedah, and we can talk for years and not discover anything. So I now have approximately 500 to 600 shots through this string and have seen more good than bad. I monitor the tips after each session, and have noticed no difference in the wear around the loop area.
With this string, which I'm told is basically a no-stretch, the bow is easy in the hand on release, and just a tad noiser than the thicker B50.
I would never suggest putting it on a priceless bow, that's why I'm giving it a good go. So far I've seen more benefits than drawbacks, and I'm not so sure the string is any harder on the bow than one that does extend the vibration after the arrow leaves the string. We will see, of course, but so far, so good. I know it's making my 45 pound Shakespeare shoot like a bow that's about 7 or 8 pounds heavier.