I will say do both. If you have a bull coming in don't fiddle with the pack. But if you are settin up take it off and you will be able to move better, if you put in the time to make sure ou can shoot with it on.
I do most of my hunts a LONG ways from the truck and just quarter or bone out and put in my daypack. I use a black creek Canadian and have hauled bears, pigs, and a whole deer and it does great and is not a bank breaker.
I think they updated it, mine has been in service for four years or so.
One thing to do on all packs is sew velrco strips on the end of the straps, 90deg to the strap, then you can keep those long straps from getting in your way.
Another thing I like is it has a orange sheet that comes out so I can relocate it when I get back from a stalk.
Nothing more annoying than spending an hou looking for a camo backpack in a brushy area, especially if your boots are with it!