Yes, there is a large spine difference in the way that you use them. On all cane, you automatically want to add 10lbs of spine to what you are looking for. This is because of the natural taper of the bamboo. You also have to add or substract 5lbs of spine, adding for anything over 28", and substracting 5lbs for anything under 28". You would do the same with point weight, add 5 lbs for every 15 grains of point weight, or substract 5 lbs for every 15 grains under.
How you place the node in relation to the strike plate is also very important. The leaf scars, the indentations at the node, have to be place at the 12 and 6 o'clock position, with the stiffest of the two sides against the strike plate.