10 lbs is quite a jump . I went from 45 @ 28, to 55 at 28 and struggled with it some. But like Ed already mentioned, everyone is different. I shoot 50 at 28, 47 @27, and i have no doubts about it putting an arrow clean through a deer with a good shot. I'm still working on the 55 @ 28 limbs. getting better everyday. I shoot the bow ok in the yard, but i know how hard it can be to draw when you have been motionless for hours and it's 20 or less out, or you have to shoot from an awkward position . 45@28 would be just fine. You will see definite improvement in performance with 5lbs more draw weight, and you can always up your weight more later. Iam making the transition to the 55 way easier after buying the 50 lb limbs. If you can, get both. I'm glad i have the heavier limbs, makes 50 feel like nothing..