Originally posted by pavan: if a pod membrane can open in flight that could be a hazard for the people that would handle the carcass or the arrow. Anectine is used as an anesthesia, it is only deadly a large doses and even then it takes a little time to work. I remember discussions way back and some thought that nicotine would be better. Pure nicotine can kill anything that it touches or anyone that touches an arrow that has it sprayed on even after it dries. We are lucky that it never got popular or legal to use it in that way. To me, an arrow that is spreading a plume of poison in flight is terrifying.