I've stated a few times in the past, I'm a two blade fan (specifically a Black Diamond Eskimo). The two blade has proven reliable for decades for me, matches the 'horsepower" that my bow produces at my poundage and 26 1/4" draw....... and its the broadhead that gives me the most confidence in the field.
The broadhead that you select should be the one that you can sharpen to a wicked sharpness and gives you the most confidence based on your specific needs. That's more important than the number of blades IMHO.