Sage,
That question is a valid one for sure.
First in some places atleast in AK, bone in is required.
Second the more cuts you make the more places bacteria can end up, considering it's not in an easy to keep dry place to begin with. I have dont it and am still up in the air if I'd do it again. Depends on the hunt really. Float moose hunt, no way! Dont have a lot of time and a long pack to meet a pickup...definatly! So I guess for me it has more to do with time (how long till the end of hunt), how far, and moisture and heat. warmer weather can create bone sour....where the center of the meat never cools before it spoils.