I live in London Ky.It took us about 7.5 hours.It was 465 miles.We went through Cincinnati on I-75 to Lima Ohio,then took US Rt. 30 to Ft.Wayne,Ind.There we took I-69 north to I-94 west to Kalamazoo.That time also took into account stopping for a quick bite to eat and also getting gas.The speed limit varied anywhere from 55 to 70 depending on where you were at as well as construction areas,etc.Not a bad drive at all.As I remember the worst traffic was in the Cincinnati-Dayton area.