First, get a map. Here in CT, the DEP has a website with air photos covering the whole state, and you can print high quality pics of the area you hunt. You can see ponds, streams, wetlands, stonewalls, atv trails etc.
Second, pound the ground. Think about getting a GPS so you can track where you've been and record way-points for important things like trails, rubs, beds, etc. When you start plotting the points, things start to fall together.
Third - spend some time in the wetlands and streams, especially in dense vegetation.
Oh yeah - and accept the fact that it just takes time to figure out a new spot - unless there is somebody local that can help you out, or you find some old tree stands that look like they were around for a while.