Should work, depending on how much centershot your bow has.
I ran GT55/75's at 30.5", with 50gr added up front, 125gr tip, from 55 and 57# @28" Blackwidows. Shot great.
But they're cut 3/16 past center IIRC, so with velcro rest they weren't too far pushed out of center.
250 up front might work, if your bow isn't cut to or past center. Ya just never know until you try (make one test arrow!).
Some people get by with setups others can't.
The more in line you are, the more spine you'll need.