If you are shooting them from the ground with a 70# bow at deer, you will have a problem. The problem will be finding your arrow because it will go so far after exiting the far side of the deer. From a tree stand, it will just be a matter of how far it will be buried into the ground.
46# Kanati, Beman ICS Bowhunter 500, 135 gr. Zwickey Delta 2 blade, 100 gr. adapter, 22.03% FOC, 22 yards, complete pass through. Exit wound is visible in this shot. The buck made it 92 of my steps from the shot. Penetration...not a problem!