I think if you are asking the question, you may already know the answer. There is no negative to having too much penetration, however you get that. If poundage is not something you can do accurately then look into a 3:1 broadhead that will give you the most advantage going all the way through the animal. In wounding/loss studies that have been conducted if you can get through the other side, you increase your chance of recovery of the animal. From my personal experience I would agree with that, 100%. Two holes having blood come out are better than one. If you encounter bone, and you probably got about a 50% chance of that, at a lower poundage the 2 blade will be helpful.