Mike, I like all my arrows to fly the same - like darts. If my nock is the right height and my arrows are spined correctly for my set-up, the arrows should all fly nock level to slightly high, bareshaft slightly weak, and all hit the target in the same group (right/left)...at least that's always been my experience.
I like to set-up some lighter flatter shooting arrows for 3d, a nice heavy one for elk, intermediate for deer, etc. I leave my brace height set the same and tune the arrows to my set-up so I can just change arrows and start shooting. Typically the nock height is the only variable in how the nock flies down range, but since I've begun experimenting with the high FOC carbons I've gotten some strange results from time to time.