I think they fly the same with any orientation, as long as they are inline with the shaft.
I prefer mine verticle - in line with the riser. When I come to full draw I glance at the head as a sort of draw check and to make sure the broadhead looks "right", just a split second glance, then focus on the target and don't look at the head.
That said, I do know, from practice, that my "point on" range is 35 yards. Helps when I'm stump shooting or practicing at long ranges - over 35 yards my arrow point has to be "over" the point I want the arrow to impact - how far over is more instinct than actual calculated gap.
Just how I do it, what works for me.