My first trad bow had both 49# and 61# limbs. I didn't have much trouble working up to the heavy limbs, being fit and strong, and doing 3 sets of 10 reps each day, drawing both left and right-handed for muscle balance. I also hold for 2-3 seconds at each draw.
As for the arrows...
Figure what weight broadheads you want to shoot, and the total arrow weight you want. These figures will shift around a bit as you zero in. Use some shaft charts to figure out what shafts will be close to fitting you. I'd recommend that you learn to tune by the 'bareshafting' method, and then work out what you need. You can probably really cut some corners by finding out what other guys are shooting with setups similar to yours, but you need to nail it down for your personal style by bareshafting (or paper tuning).
Since your form is probably not perfect yet, don't forget that as your muscles harden, as your draw length stabilizes, and your releases become more consistent, your arrows could start flying differently. You'll then want to refine your tuning setup again.