Hi Jim,
I prefer my broadheads mounted at a 45 degree angle. I cut my arrows so the back of the broadhead touches my bow hand when I reach full draw. This allows me to use the arrow as a draw check of sorts (had some issues with target panic...this helps keep it from coming back!). The 45 degree angle also keeps the broadhead blades out of my sight picture. That's my preference, but to each their own. Get 'em tuned up properly and they'll fly well whichever orientation you put them in.
Cheers, Matt