I think it'd be no difference. Also they sell the 50grain insert weights that screw into the back of the insert from the nock end.
I use them on all my carbons and I love them. It's a bit of an investment initially, but now I only have to buy 125grain broadheads. I've got a pile of the brass insert weights in 20 and 50 grains and use them to adjust teh total point weight. I've used them with the GT 100 grain brass inserts and the normal GT aluminum inserts with good success. They work on other inserts as wella s long as there threaded all the way through to the back of the insert. otherwise you'll have to run a a tap through the insert.