With a two blade, I have found that it makes no difference how it aligns with the fletch, providing it is spinning true, with no wobble. Three or four blade(from my wheelie days) did need to be aligned and spun. I would think either of those fletch combos would work well...are you using a helical or straight? Helical would stabilize a bit better. Of course, I am new to woodies, and this is just what I have found out making my own arrows in the last year or so...
Good luck either way!