I do, left handed, I use it right handed on long shots. At first, when I went to primarily shooting lefty, I could get my eyes confused from left to right, but after a while it became natural. The one thing that Hill states over and over that this an 'imaginary, indirect aiming point'. he also stated that one can get too 'dogmatic' in explaining it. After a few million shots it will become second nature and will seem more instinctive, but the basics of how you point the arrow will still be there. I think some very good purly instinctive shooters do this, even though they claim that they do not 'see' the arrow it is there right in front of them and it is a very familiar image. The acknowledgement is not one of conscious deliberating, more of a natural responce to what their eyes see. Hill puts it all in more graphic terms and claims to be consciously aiming, even though it appears to be nearly instantanious. I think that it is important to consciously point the arrow in the last few inches of draw, but at close quick shots, for me, getting very fundamental with the aim, would require that every shot would have to be in the exact same positions, which is nearly impossible when hunting. For odd position shots, the imaginairy secondary aiming point will put you in the ball park. Then, at some point the accurate shot would be aimed with the impression of where the arrow is and the final complex number crunching done at a very fast intuitive level.