As Katman said, it really comes down to the particular bow.
What happens is that at a certain weight, the stiffness of the limbs causes additional flex through the riser, which lowers the efficiency.
On the other side, you will lose efficiency to extra string mass, limb and tip mass, etc. on lighter models. This also depends on the design, which is why many bows have a "sweet spot".
They're very small differences, usually, and normally anyone shooting 45-60# will be pretty darn close to "optimal".