From my LIMITED medical experience, our own Tarz nailed it...
KNapped edges are grosely serrated, true, but each serration is smooth as ...well, GLASS!
IF the medical community prefers a honed edge for surgery, I go with that...
A Ragged tear in an artery, as some noted, picks up the platelets and clots faster. I don't want archery shot deer wounds to clot fast, I want them to bleed hard!!!
One of the reasons I heard was that a 2 blade smooth cut seals up too quickly... sure, until the critter moves a bit...
We, as hunters, will always rely on our own logic to make choices... and as such, "to each his own".