I really enjoy the Kanab 2.0. I haven't tried the Guide Pant though. I wear mine with the Allegheny bottoms (basically long johns), and have chased elk (first time) and been stand hunting for deer the past three weekends. They are a great pant. Love the fit, the second pocket in the right front fits wind detector bottles nicely, the way the front cargo pockets are made you have a Really Nice bow tip holder for 'ready to draw' positioning of your bow. The back pocket zips close, which I like for holding my license at all times. The hand pockets are very deep and seem to ride on the front of the leg just above the cargo pockets (little overlap), which feels great as items are not bouncing around when you walk.
If you go Kanab, make sure it is the Kanab 2.0, it has these features, the older style do not. Looking to sell my originals and get another pair of 2.0's.