If you are drawing to 28" or even somewhat less, you can count on killing anything on the continent with that setup assuming you put the arrow where it needs to go.
I'm not personally a fan of three blade heads. I've used them and prefer two or two with a bleeder simply because I find it easier to get them scary sharp. If you are one of those who can do that with a three blade head, then I see no reason not to use them. I've killed stuff with snuffers and woodsman broadheads, but I can get Deltas, Simmons Tiger Sharks, and Stingers way sharper.