Hmmmm. Depends on how you want to use it. I have a Bison Gear Lost River, which is a bit smaller. I use it as a day pack, and it carries all I could ever need for that purpose. Though the pack itself is quite light, the contents can get quite heavy though, so when used as a day pack, it's usually only about 1/2 to 2/3 full.
I think the Selway would work well for two-3 day sojourns away from base camp (though with all the the tie-on straps, the Lost River would probably suffice for that purpose as well). I personally think the Selway a bit small to carry everything in on your back for an extended week long hunt, but I suppose that depends a little on how lightly you pack.
I'm less that 6 feet tall so can't speak to the fit issue at your height, but the straps are as versatile as any I've seen, the waist belt rides where it should and the pack is very comfortable on me.
Pretty sure the 2,200 cubic inches is the combined volume of all of the pack's parts.