Mostly, I shoot wooden bows off the shelf, so I don't worry about this, but my Das Dalaa has an adjustable strike plate. I've always just left it alone, where they set it at the factory. It is set so that the tip of the arrow is a little to the left of the bow's center, which seems to be the recommended place where it should be.
However, I assume they made it adjustable for some purpose. Would there be any advantage to fooling around with this, and what should I look for if I move it in a little closer to centershot, or move it a little further out?