I made the switch a few years ago. Left eye dominant/right handed. The sight picture is very different when not shooting from your dominant eye side. Dominant eye is straight down the arrow, non dominant, the arrow is cocked at an angle. I actually quit shooting as I couldn't get consistent.
I guess you're not supposed to see the arrow, just the "spot", but it's hard to ignore. I found the little things the toughest. Right from the get-go I liked the look/feel of the arrow and the shot. But trying to nock an arrow with a non dominant hand/fingers was frustrating. Same with getting an arrow out of the quiver. After 1000 times, it's much easier and now the other way is long forgotten. The sight picture is as it should be.