A 2016 w/ 125 gr. point out of a 50# bow should be fairly close to the correct spine if you have about a 28" draw, but as McDave suggested your string nock may be too low and the shaft may be striking the shelf. Try raising the nock 1/8" to a 1/4".
Silencer placement on the string or type of material used can contribute to noise. Fur strips can 'buzz' if they get loose, and most any silencers placed too close to the loops can be ineffective.
If still noisy, try raising brace height by 1/4" to 1/2"...sometimes the recommended specs don't work for a given bow.
If still noisy, check the tiller measurements from the string to the riser fadeouts on both top and bottom limbs. For 3-under shooters bows tend to like even to 1/8" positive (i.e., distance is the same or 1/8" more for the top limb than for the bottom). If shooting split fingered a 3/16" to 1/4" positive tiller (top limb) should work. If the tiller is off for your shooting style that might contribute to extra noise.
Finally, be sure your limbs are aligning properly by sighting down the length of the string with the bow strung. If a limb seems a bit crooked, 'bump' it back into alignment by unstringing the bow and twisting the limb in the opposite direction of the bend, holding it there briefly. Then restring the bow, check for limb straightness, and if it's ok shoot and check for noise again.
It's unlikely that all of this stuff is a problem but any one of them might be. Checking them one at a time might help determine the culprit by the process of elimination.
Hope this helps.