To tenderize a brisket, it needs to get to 190 -195 internally. I don't know about the pink salt to tenderize it. I know that when Deli's cook pastrami, they rub/cure them, then smoke them, then put them in a steamer to get them tender. Not sure if they smoke them long enough to get to 190-195, or just enough to get a light smoke flavor profile. Pretty sure the steaming process get them tender.
You might try a rub/cure, light smoke, then put the brisket on a rack in a deep pan, with some liquid (beer, cider, water, etc...) on the bottom. Cover tight with foil and place in a 350 oven for about 3 hours. Check for tenderness.