I have killed a bunch of stuff over there. My biggest animal was a 54" kudu, but I have also killed waterbuck, gemsbuck, red hartebeest, and nyala. All with a 50#@my29" draw bow and 550ish grain arrows. I also shoot FMJ's, but I use the brass HIT inserts. You will have no issues killing critters with either setup if you are well tuned and put them in the right place. I would say shoot the one that you shoot best, and have the most confidence in.
Bisch