Scott, there are a lot of formulas out there, but my own personal one is that I like 50# of anvil for each pound of hammer.
My anvils are 157# and 167# and seem to be really active up through my three pound hammers. After that it's just really obvious that I'm throwing too much hammer for the anvil to return on the bottom side.
Don't forget that every time you hit you work piece, it's getting smacked on the bottom side by the anvil, but only if you're not sending so much energy at it that it just sort of zooms right on through.
The type of steel has a lot to do with how the anvil performs, some are iron, some are poured and some are forged.
I want a 300#er. That way ALL! of my energy is induced into the workpiece.
The heavier your anvil, the less work you have to do.