Yes,
We recently had a city deer killed by a pack of yotes. A local wildlife service guy. (Glorified pest control) was speculating that it was a wolf. He was going by the size of the tracks and the condition of the carcass. Of course, he didn't think about the track melting or the fact that maybe it was a pack of yotes, or that the deer was injured by a car first or something. The last time there was a wolf around here was before there were settlers. Of course, then folks all over town were calling in "wolf" sightings.
Luckily, the mayor ain't buyin' it. The yotes are simply being pushed out of the woods by construction equipment. Hey, they gotta eat too!
You tear down enough habitat and limit enough hunting, these things happen.