I don't see a problem Nick, if you mean at the riser? Bamboo seems to hold a deep reflex, without glass just fine.
Over the past 10 or so years, I have seen some pretty radical limbs with all wood or bamboo, done.
What do you perceive would be a problem?
I haven't done anything more elaborate than sinew backing on all wood. I have alot of intentions though!
But really, there is no set rules when it comes to bows, as I see it. Just fun!