There’s a few factors here. Wind direction should be the first. It’s impossible to be only one direction but if that’s your preferred or needed wind you need to consider other options. Are the deer coming above you down, are they coming up from down, does the cover force a turn, how is the cover, what kinda tree?
After you ensure they can’t smell you you next gotta make sure they can’t see you and you can shoot. It’s that simple and there’s no exact answer, it depends on that set up