I lean toward the Ashby camp. 650+ grains, lots of FOC. But I probably overcompensate from lack of much personal experience.
On the one hand, I appreciated that my arrow buried itself to the fletching on my turkey this year, even though the broadhead was dull from being shot into the dirt earlier that day. Couldn't shave a single hair off and it still soaked the fletching in blood.
On the other hand, maybe I wouldn't have buried a few arrows in the dirt under those turkeys if they were a little lighter and faster...