Fujimo gets it... to a point. Hi Wayne
It wouldn't matter to most folks, since most don't balance their limb's strengths relative to the shooter... BUT even within those that do... design/bow center location is quite relevant. Those that design their bows symmetrical because they think it makes it easier for them to gauge tiller aren't seeing the big picture. Exact center location can be what separates a really good bow from a great one.
In a bow of asymmetrical design, with the top limb about 1 1/2" longer than the bottom for instance, the bow's center can be precisely where the three under shooter's string hand fulcrum is located. This is the easiest design of bow, and string hold, to perfectly balance both statically and dynamically... that is, from carrying, to the very beginning of the draw through to the end, the best balanced and sweetest drawing and shooting bow there is. imo. If the bow hand grip is held neutral, not high or heeled, there is no fulcrum shift during the draw. Zero. Unfortunately I shoot split, so my bows aren't as perfectly balanced as these, but they're pretty dang close
It's really, really hard... no, virtually impossible to make a symmetrical bow with all of these qualities.