Tom,
I went down in draw weight to a 45 pound Martin Hunter this year. Shooting CE Heritage 150's, 160g STOS with a 40 g adaptor, for a total arrow weight of 550 g. My EFOC is 19% which, according to Dr. Ashby, is on the low end of EFOC. I've found that I'm shooting much better also with the lower weight.
Shot three deer so far this season. Two bucks both field dressed 180# and a doe that I'll probably get 2 or 3 sammiches out of.
One, 12 yards, broadside through the heart, complete pass-thru. Second buck, 20 yards, hard quartering away shot in the ham/femoral, did not pass thru. And lastly the "2 sammich doe", 20 yards, quartering away, entered between the 3rd and 4th rib from the back, exited out the opposite leg and broke it.
So, 45 pounds is plenty for deer as far as I'm concerned. Plus I can practice more shooting the lower weights, which is a good thing. I also like a heavy 12 gpi arrow and the relatively high FOC. YMMV.