Best advice
1) Don't try to do too much. Alaska is 5 times the size of California, no way your going to do it all in one trip.
2) Get away from the road system, unless you love crowds it is the only way your going to enjoy fishing here.
3) Stay flexible never can tell when momma nature will destroy the best laid plans of you and the wife
4) As with any travel hook up with a local if you can, we know the good places, restaurants and how to get away from the crowds.
I'm in Palmer drop me a PM if you'll be passing through, you'll find long time Alaskans are friendly to a fault. If you do find yourself in Homer Dave is the guy to talk to, and a good friend of mine. Like Fletcher I wouldn't combat fish if my life depended on it, however there are ways to avoid the crowds, and places to fish in peace.