This seems to me very much like the "shotgun" debate-which one shoots best. We have similar factors at work here, primarily being bow fit to enable you to draw to a consistent anchor point each time, and arrow tuning. When I'm working up a specific load for one of my scatterguns, I'm looking at pattern results based on, essentially, tuning the round to the gun/forcing cone/choke combo. We're tuning our arrows and heads to get the most consistent flight from the bow as well. The difference comes in building a custom shotgun, having it precisely fitted to one's gun mount. I don't know any bowyers who go to that length to get a bow to precisely fit it's owner. We tend to spend money on pretty risers, and there's no consideration given to grip, length of pull, etc. I'm willing to bet you'll find some bows will fit your palm/draw better than others, and will allow a more consistent draw.
That being said, most of us have more than one bow, and since we shoot `em all, tend to be less intimately familiar with all of them, than if we only shot one bow, all the time.