I once reshaped the grip on a Brackenbury bow using a drum sander so my hand was closer to the shelf. I thought that it would affect the tiller less if I reshaped the grip than if I altered the position of the shelf. However, whenever you change the position of the pressure point of your hand on the bow, you're affecting the tiller, so I'm sure I changed the tiller some anyway. After changing the Brackenbury, I never felt like doing that again. I buy bows that are set up to shoot off the shelf from bowyers who know what they're doing, so I concluded that it was probably stupid for me to think that I could engineer the bow better than they did. Sort of the same reason I don't make my own wine.
It reduces a variable when shooting instinctively if the arrow is closer to your hand, as it minimizes the swing of the front of the arrow back and forth as you change the cant of your bow. Bear in mind that you would probably move the pivot point of the bow closer to the arrow by switching from a low wrist grip to a high wrist grip than you would by reworking the grip and shelf. But if your high wrist grip wasn't as strong as your low wrist grip, your overall accuracy might suffer from the change. As long as you're shooting from your preferred cant, your brain will adjust and a small distance from the arrow to your hand shouldn't matter. It's just when you vary that cant that errors would be reduced if the arrow were closer to your hand.