Wondered something similar, but I'm not fortunate enough to have access to the variety of bows required to test the theory. I have two 60", 46# @ 28" Morrisons, an A/D Shawnee and an A/D Cheyenne. My perception is that they have noticeably different shooting "characteristics", but my guess is that most of that is reflex vs. deflex design. I go through spells where I favor one over the other, but shoot them both equally well with practice. I like mass in a riser and the Cheyenne is Cocobolo Dymondwood whereas the Shawnee is Bocote/Macassar. I think the A riser Cheyenne is 1" longer than the Shawnee to begin with so my comparsion isn't really apples to apples anyway. But my question is would there likely be a perceptible difference from a different 60" combination (B-riser, C-limb), with all else equal, i.e. poundage, limb design/composite, string, etc. ?