25 yards with a 380 gr. carbon arrow with a long bow! I'll tell ya what, heres what ya do, set up some phone books at 10, 15, 20, 25 yards shoot at them notice your penitration depth at each yardage then decide. 10, 20 yards max in my opinion and 20 is with perfect conditions with a 550gr. arrow, besides i like seeing the hair on their nose, getting close is the key, besides the last buck, last year, that i shot dressed out at 242lbs. Hit a buck like that squarely in a rib at 25 yards and you might run into problems.Jonesy