Well here is my experience, draw from it what you like...
I shot a bull at 22 yds with a 77# BW longbow and a 695 gr. carbon arrow tipped with a buzz cut stinger (2 main blades and a bleeder). On a 3D target my shot would have been an 8 but it was high.
I must have hit a rib square cause the arrow only penetrated 10 inches or so.
We found very little blood and never found the bull.
We heard him coughing/choking and the blood we found clearly showed a lung hit but with only one hole in him he did not leave enough blood to follow him very far.
To do it over again, I would have been shooting a true 2 blade head with hopes to get in a little deeper.
My guide told me about a hunter he had a few years prior shooting a 53# recurve and got a complete pass through. The bull died within 100 yds. I would guess his arrow had no/minimal contact with bone.
Good luck on your hunt!