Piebalds should not be protected by hunters.
From a quick search, the Virginia DNR has a FAQ on piebalds and here's their answer...
Unlike true albinos, piebald deer have brown eyes and black hooves. The piebald condition is frequently associated with other harmful physical conditions, including skeletal deformities (e.g., dorsal bowing of the nose, short/deformed legs, curved spine, short lower mandible, etc.) and internal organ deformities. Piebald deer are rare, typically occurring at less than one percent of the population. Piebald deer can be more common on a local basis, especially in areas where deer hunters protect them. Piebald deer are not afforded any special protection by Department regulation, and the Department does not recommend these animals be protected.
The other kind of white deer are true albinos. Unlike piebald deer, these deer are normal except for lacking the gene(s) for color. True albinos have pink eyes and white hooves. These deer are rare with just a couple killed annually by deer hunters in Virginia. Like piebald deer, albino deer are not afforded any special protection by Department regulation, and the Department does not recommend these animals be protected.
From another quick search...
A piebald deer is a deer with a brown and white spotting pattern which is not caused by parasites or diseases. They can appear to be almost entirely white. In addition to the non-standard coloration, other differences have been observed: bowing or Roman nose, overly arched spine (scoliosis), long tails, short legs, and underbites.
Piebald deer (partially white) are from a recessive genetic trait and the deer usually become more prevalent due to overpopulation of a deer herd.