A Craig Barr forged blade made of 52100 steel may be the one that stays the sharpest under hard use. I have the 2012 St. Jude auction bowie knife that Doug Campbell made from 52100, and it is also amazingly sharp, but I haven't used it for cutting up game. There are lots of great steels that will make amazing blades if they are properly designed, constructed and heat-treated, but that is no small task. There are some fantastic knife makers on this site who can put together outstanding knives that will do anything a fellow could reasonably expect a knife to do and do it well.
Allan