The only time it matters is if you shoot off your hand ( to stop from getting cut) and not the shelf or rest. The arrow does not start to rotate until after it has left the bow and a well tuned set up will have very little fletch contact. So its what ever torques your cookie. Im right handed and shoot right wing. Some 30 odd years ago when i first started and had no one to ask, i thought , im right handed so right wing would be for me and now that all my fletching tools are right wing i never have tried left and have had no reason to.